Карточка-задание по английскому языку на тему «MEDICAL WRITING: CASE ABSTRACT_150»
«MEDICAL WRITING: CASE ABSTRACT_150»
·What is a medical case report?
·What parts does it include?
·What is an abstract?
Read the abstract of the medical case
disease with pulmonary mass-like opacities secondary to hypersensitivity
pneumonitis: a case report
Chronic granulomatous disease, one
of the primary immunodeficiency syndromes, is characterized by failure of
phagocytic capacity due to loss of reactive oxygen species production, as well
as formation of granulomas in organs. Clinically, dysregulated inflammation by
excessive cytokine production due to loss of reactive oxygen species production
is suggested as a cause of noninfectious inflammatory problems such as chronic
granulomatous disease colitis. We experienced a rare case of a patient with
chronic granulomatous disease with unique pathological and radiological
presentations of hypersensitive pneumonitis, which to our knowledge has never
been previously reported.
A 20-year-old Japanese man with
chronic granulomatous disease was referred due to cough and abnormal chest
imaging findings. Computed tomography of his chest showed diffuse, bilateral,
centrilobular nodules and multiple mass lesions in lower lobes that do not fit
a common image of hypersensitivity pneumonitis. Pathological findings of both
nodules and mass lesions on surgical lung biopsy were homogeneous, and
excessive granulomas in the bronchioles and alveolar duct as well as lymphocytic
alveolitis were seen, all consistent with hypersensitivity pneumonitis. The
radiological and laboratory abnormalities did not improve after antigen
avoidance; however, they disappeared after high-dose steroid therapy.
When we encounter a case of
hypersensitive pneumonitis showing atypical pulmonary mass-like opacities in a
patient with chronic granulomatous disease, we should consider
hyperinflammatory status and excessive granuloma formation of chronic
granulomatous disease and start with high-dose steroid therapy as treatment.
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·Why is it important
·Needs to be reported
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1.Is this the first report of this kind in the literature?
2.What are brief details of what the patient(s) presented with?
3.What the reader should learn from the case report?
4.What the clinical impact will be?
5.Is it an original case report of interest to a particular clinical
specialty of medicine?
6.Will it have a broader clinical impact across medicine?
7.Are any teaching points identified?
·Why abstract is the most important part for case
published in electronic databases?