Карточка-задание по английскому языку на тему «MEDICAL WRITING: CASE ABSTRACT_58»
«MEDICAL WRITING: CASE ABSTRACT_58»
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Testicular seminomatous mixed
germ cell tumor with choriocarcinoma and teratoma with secondary somatic
malignancy: a case report
Testicular tumors are a
heterogeneous group of neoplasms exhibiting diverse histopathology and can be
classified as seminomatous and non-seminomatous germ cell tumor types. Mixed
germ cell tumors contain more than one germ cell component and various
combinations have been reported. Here, we present a rare case of a mixed germ
cell tumor composed of seminoma, choriocarcinoma and teratoma with a secondary
A 31-year-old Caucasian man
presented with splenic rupture to our hospital. A right-sided testicular
swelling had been present for 6 months and his alpha-fetoprotein, beta-human
chorionic gonadotropin, and lactose dehydrogenase were increased. An ultrasound
of his scrotum revealed an enlarged right testis with heterogeneous
echogenicity. Multiple hypervascular lesions were noted in his liver and
spleen. He underwent transcatheter embolization therapy of his splenic artery followed
by splenectomy and right-sided orchiectomy. A computed tomography scan also
showed metastasis to both lungs. During his last follow up after four cycles of
cisplatin-based chemotherapy, the level of tumor markers had decreased,
decreases in the size of his liver and pulmonary lesions were noted but new
sclerotic lesions were evident in his thoracolumbar region raising concern for
Prognosis of testicular tumor
depends mainly on the clinical stage, but emergence of a sarcomatous component
presents a challenge in the treatment of germ cell tumors and the histological
subtype of this component can be used as a guide to specific chemotherapy in
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