Карточка-задание по английскому языку на тему «MEDICAL WRITING: CASE ABSTRACT_404»
«MEDICAL WRITING: CASE ABSTRACT_404»
·What is a medical case report?
·What parts does it include?
·What is an abstract?
Read the abstract of the medical case
cyclophosphamide therapy: a case report
Cardiac toxicity is one of the
life-threatening complications of cancer therapy. Systemic anticancer
treatments may exert their own toxic effects or can aggravate adverse effects
of other drugs. We report a case of cyclophosphamide-induced cardiotoxicity in
a patient with normal cardiac functions before chemotherapy.
A 66-year-old Caucasian woman with
a mediastinal mass diagnosed with Burkitt lymphoma underwent chemotherapy with
On the seventh day of chemotherapy, she developed dyspnea. An electrocardiogram
demonstrated low voltage in the limb and precordial leads. It also showed diffusely
increased myocardial echogenicity, mild pericardial and pleural effusion,
generally impaired biventricular systolic functions with a left ventricular
ejection fraction of 31%, and right ventricular mid-apical akinesia, even
though she had normal biventricular functions before chemotherapy.
Cyclophosphamide-induced cardiotoxicity was suspected and she was given
treatment for congestive heart failure. Her dyspnea decreased and she was
discharged on the tenth day with a left ventricular ejection fraction of 37%
and normal right ventricular function. After 1 month, echocardiography showed
normal biventricular functions with a left ventricular ejection fraction of
therefore, should be taken into consideration when using cyclophosphamide
therapy, especially when anthracyclines are co-administered. Close
communication between hematologists and cardiologists is required.
Find in the abstract:
·Why is it important
·Needs to be reported
Answer the questions:
1.Is this the first report of this kind in the literature?
2.What are brief details of what the patient(s) presented with?
3.What the reader should learn from the case report?
4.What the clinical impact will be?
5.Is it an original case report of interest to a particular clinical
specialty of medicine?
6.Will it have a broader clinical impact across medicine?
7.Are any teaching points identified?
·Why abstract is the most important part for case
published in electronic databases?