Карточка-задание по английскому языку на тему «MEDICAL WRITING: CASE ABSTRACT_411»
«MEDICAL WRITING: CASE ABSTRACT_411»
·What is a medical case report?
·What parts does it include?
·What is an abstract?
Read the abstract of the medical case
Oculomotor nerve palsy
associated with bortezomib in a patient with multiple myeloma: a case report
Bortezomib is a proteasome
inhibitor used in the treatment of multiple myeloma. A newly recognized
oculomotor nerve palsy related to bortezomib is described.
A 54-year-old Caucasian woman with
immunoglobulin G kappa multiple myeloma on single-agent bortezomib given by
intravenous push once weekly developed isolated unilateral partially reversible
left sided oculomotor nerve palsy during the first cycle of treatment. All the
essential diagnostic tests that were carried out excluded all other possible
causes. There was a positive dechallenge-rechallenge test. Management was by
withdrawal of bortezomib and empirical dexamethazone. To the best of our
knowledge, this is the first report of its kind in the literature.
This case illustrates the probable
association between oculomotor nerve palsy and bortezomib, and generates a
hypothesis of whether bortezomib can cross the blood-brain barrier or not.
Find in the abstract:
·Why is it important
·Needs to be reported
Answer the questions:
1.Is this the first report of this kind in the literature?
2.What are brief details of what the patient(s) presented with?
3.What the reader should learn from the case report?
4.What the clinical impact will be?
5.Is it an original case report of interest to a particular clinical
specialty of medicine?
6.Will it have a broader clinical impact across medicine?
7.Are any teaching points identified?
·Why abstract is the most important part for case
published in electronic databases?