Карточка-задание по английскому языку на тему «MEDICAL WRITING: CASE ABSTRACT_474»

КАРТОЧКА-ЗАДАНИЕ НА ТЕМУ

«MEDICAL WRITING: CASE ABSTRACT_474»

Warm-up

·         What is a medical case report?

·         What parts does it include?

·         What is an abstract?

Read the abstract of the medical case report:

Agranulocytosis and hepatic toxicity with ticlopidine therapy: a case report

Abstract

Introduction

Ticlopidine is a platelet inhibitor used to prevent thrombosis in patients with cerebrovascular or coronary artery disease. The most common side effects are mild and transitory: diarrhea, dyspepsia, nausea and rashes. More serious, but less frequent, adverse effects are hematological dyscrasia and cholestatic hepatitis. We report a rare case of agranulocytosis associated with hepatic toxicity, probably related to the use of ticlopidine.

Case presentation

A 70-year-old Caucasian woman, with no previous history of hematological or liver diseases, was treated with ticlopidine 250 mg twice daily immediately after a vertebrobasilar stroke. Upon admission, her blood tests were normal. About four weeks later she developed agranulocytosis and hepatic toxicity. Ticlopidine was discontinued immediately, and aspirin 25 mg and dipyridamole 200 mg were given twice daily. She was treated with hematopoietic growth factors (granulocyte colony stimulating factor), with a rapidly increased white blood count and progressive normalization of liver tests as a result.

Conclusion

In the first three months following initiation of ticlopidine therapy, regular monitoring of complete blood cell count and of liver function tests is essential for the early detection of serious and unpredictable side effects.

Find in the abstract:

·         Background

·         Why is it important

·         Needs to be reported

Answer the questions:

1.       Is this the first report of this kind in the literature?

2.       What are brief details of what the patient(s) presented with?

3.       What the reader should learn from the case report?

4.       What the clinical impact will be?

5.       Is it an original case report of interest to a particular clinical specialty of medicine?

6.       Will it have a broader clinical impact across medicine?

7.       Are any teaching points identified?

Follow-up

·         Why abstract is the most important part for case published in electronic databases?

·         What are basics of abstract writing?