КАРТОЧКА-ЗАДАНИЕ НА ТЕМУ
«MEDICAL WRITING: CASE ABSTRACT_234»
Warm-up
· What is a medical case report?
· What parts does it include?
· What is an abstract?
Read the abstract of the medical case report:
Thyroid carcinoma and primary amenorrhea due to Mayer-Rokitansky-Küster-Hauser syndrome: a case report
Abstract
Introduction
This case report describes an association between an exceptionally rare congenital anomaly and differentiated thyroid carcinoma. Mayer-Rokitansky-Küster-Hauser syndrome is characterized by vaginal aplasia associated with other Müllerian duct abnormalities. Its penetrance varies, as does the involvement of other organs. The association with thyroid carcinoma appears to be exceptionally rare, and warrants further attention.
Case presentation
We present the case of a 19-year-old Caucasian woman with amenorrhea and thyroid disease, with an unusually late diagnosis of gynecological abnormality. Management of her amenorrhea included investigation for congenital anomalies, including Mayer-Rokitansky-Küster-Hauser syndrome. Endocrine evaluation included a detailed analysis of sex hormone levels and thyroid function. The results of a physical examination and neck ultrasonography revealed abnormalities of the thyroid gland, which led to a diagnosis of thyroid cancer. To the best of our knowledge, thyroid cancer has not previously been reported in association with Mayer-Rokitansky-Küster-Hauser syndrome. However, genetic links between Mayer-Rokitansky-Küster-Hauser syndrome and thyroid cancer have not been investigated. The association may therefore be coincidental.
Conclusions
All women with primary amenorrhea should undergo complete investigation of the genital tract and the endocrine axis. Careful examination of the thyroid gland is recommended.
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· Background
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3. What the reader should learn from the case report?
4. What the clinical impact will be?
5. Is it an original case report of interest to a particular clinical specialty of medicine?
6. Will it have a broader clinical impact across medicine?
7. Are any teaching points identified?
Follow-up
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