Карточка-задание по английскому языку на тему «MEDICAL WRITING: CASE ABSTRACT_24»
«MEDICAL WRITING: CASE ABSTRACT_24»
·What is a medical case report?
·What parts does it include?
·What is an abstract?
Read the abstract of the medical case
A case of polyarteritis nodosa
limited to the right calf muscles, fascia, and skin: a case report
Limited polyarteritis nodosa is a
rare benign disease that usually responds well to systemic corticosteroid
treatment. We report a case limited to calf muscles, fascia, and skin treated
with local corticosteroid therapy directed to the affected areas by ultrasound
A 36-year-old Caucasian woman
presented with a 10-month history of progressive right calf pain and swelling,
which were unresponsive to treatment with non-steroidal anti-inflammatory drugs
and physiotherapy. An examination revealed a swollen tender right calf with
indurated overlying skin. Laboratory investigations showed an erythrocyte
sedimentation rate of 24 mm/hour and a C-reactive protein of 15 mg/dl. Full
blood count, renal profile, and creatinine kinase level were normal. A full
autoantibody screen and hepatitis B and C serology results were negative. A
chest X-ray was unremarkable. Magnetic resonance imaging of the right leg revealed
increased signal intensity in T2-weighted images and this was suggestive of
extensive inflammatory changes of the gastrocnemius muscle and, to a lesser
extent, the soleus muscle. There were marked inflammatory changes throughout
the gastrocnemius muscle and the subcutaneous tissue circumferentially around
the right lower leg. A biopsy of affected skin, muscle, and fascia showed
histopathological features consistent with polyarteritis nodosa, including
small-vessel vasculitis with fibrinoid changes in the vessel wall and intense
perivascular and focal mural chronic inflammatory changes. Our patient declined
treatment with oral steroids. She received a course of ultrasound-guided
injections of steroid (Depo-Medrone, methylprednisolone) in the involved muscle
area and commenced maintenance azathioprine with a good response.
Limited polyarteritis nodosa is
rare and affects middle-aged individuals. In most cases, treatment with
moderate- to high-dose corticosteroids gives symptomatic relief within one
week. Resistant cases require treatment with cytotoxics or intravenous
immunoglobulins. This case demonstrates response to local targeted steroid
therapy as an alternative to systemic steroids.
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·Why is it important
·Needs to be reported
Answer the questions:
1.Is this the first report of this kind in the literature?
2.What are brief details of what the patient(s) presented with?
3.What the reader should learn from the case report?
4.What the clinical impact will be?
5.Is it an original case report of interest to a particular clinical
specialty of medicine?
6.Will it have a broader clinical impact across medicine?
7.Are any teaching points identified?
·Why abstract is the most important part for case
published in electronic databases?