Карточка-задание по английскому языку на тему «MEDICAL WRITING: CASE ABSTRACT_39»
«MEDICAL WRITING: CASE ABSTRACT_39»
·What is a medical case report?
·What parts does it include?
·What is an abstract?
Read the abstract of the medical case
A case of limbic encephalitis
presenting as a paraneoplastic manifestation of limited stage small cell lung
cancer: a case report
The differential diagnosis of
altered mental status and behavioral change is very extensive. Paraneoplastic
limbic encephalitis is a rare cause of cognitive impairment, which should be
considered in the differential diagnosis.
A 64-year-old British Caucasian
woman presented to our hospital with a 12-week history of confusion and
short-term memory loss. She was hyponatremic with a serum sodium level of
128mmol/L. Moreover, there was evidence of left hilar prominence on the chest
radiograph. A thoracic computed tomography scan showed left hilar opacity with
confluent lymphadenopathy. A percutaneous biopsy confirmed a diagnosis of small
cell lung cancer. There was no radiological evidence of brain metastasis on the
computed tomography scan. In view of continued cognitive impairment, which was
felt to be disproportionate to hyponatremia, a magnetic resonance imaging scan
of the brain was undertaken. It showed hyperintense signals from both
hippocampi, highly suggestive of limbic encephalitis presenting as a
paraneoplastic manifestation of small cell lung cancer. She had a significant
radiological and clinical response following chemotherapy and radiotherapy.
This case highlights the
importance of considering paraneoplastic syndromes in patients with
neurological symptoms in the context of lung malignancy. If initial
investigations fail to reveal the cause of cognitive impairment in a patient
with malignancy, magnetic resonance imaging may be invaluable in the diagnosis
of limbic encephalitis. The clinical presentation, diagnostic techniques and
management of paraneoplastic limbic encephalitis are discussed in this case
Find in the abstract:
·Why is it important
·Needs to be reported
Answer the questions:
1.Is this the first report of this kind in the literature?
2.What are brief details of what the patient(s) presented with?
3.What the reader should learn from the case report?
4.What the clinical impact will be?
5.Is it an original case report of interest to a particular clinical
specialty of medicine?
6.Will it have a broader clinical impact across medicine?
7.Are any teaching points identified?
·Why abstract is the most important part for case
published in electronic databases?