Карточка-задание по английскому языку на тему «MEDICAL WRITING: CASE ABSTRACT_420»

КАРТОЧКА-ЗАДАНИЕ НА ТЕМУ

«MEDICAL WRITING: CASE ABSTRACT_420»

Warm-up

·         What is a medical case report?

·         What parts does it include?

·         What is an abstract?

Read the abstract of the medical case report:

Late-onset benefit in progressive advanced hepatocellular carcinoma with continued sorafenib therapy: a case report

Abstract

Introduction

In the past, no effective systemic therapy has existed for patients with advanced hepatocellular carcinoma. Sorafenib, an oral multikinase inhibitor, has recently been shown to improve overall survival in patients with advanced hepatocellular carcinoma in two randomized, double-blinded, placebo-controlled trials. This drug has been approved as the first-line therapy for advanced hepatocellular carcinoma patients. We report an intriguing case of advanced hepatocellular carcinoma in which the patient achieved late- onset partial response by prolonged administration of sorafenib in spite of progressive disease.

Case presentation

A 54-year-old Japanese man was treated with sorafenib for multiple lung metastases after surgical resection for advanced hepatocellular carcinoma accompanied by vascular invasion of the left branch of the portal vein. Although the effective diagnosis was progressive disease, almost all sites began to reduce or disappear eight months after the diagnosis of progressive disease. A dramatic reduction in alpha-fetoprotein and des-gamma-carboxy prothrombin levels was observed. The patient finally achieved partial response and his status remains unchanged.

Conclusions

If tolerated, prolonged sorafenib treatment may be beneficial.

Find in the abstract:

·         Background

·         Why is it important

·         Needs to be reported

Answer the questions:

1.       Is this the first report of this kind in the literature?

2.       What are brief details of what the patient(s) presented with?

3.       What the reader should learn from the case report?

4.       What the clinical impact will be?

5.       Is it an original case report of interest to a particular clinical specialty of medicine?

6.       Will it have a broader clinical impact across medicine?

7.       Are any teaching points identified?

Follow-up

·         Why abstract is the most important part for case published in electronic databases?

·         What are basics of abstract writing?