Карточка-задание по английскому языку на тему «MEDICAL WRITING: CASE ABSTRACT_331»

КАРТОЧКА-ЗАДАНИЕ НА ТЕМУ

«MEDICAL WRITING: CASE ABSTRACT_331»

Warm-up

·         What is a medical case report?

·         What parts does it include?

·         What is an abstract?

Read the abstract of the medical case report:

Primary uveal lymphoma effectively managed with oral chlorambucil: a case report

Abstract

Introduction

Ocular lymphomas account for five to 10 percent of all extra-nodal lymphomas. Primary uveal lymphoma is quite a rare entity and usually unilateral. We present a case of a primary uveal lymphoma with conjunctival and orbital extension, successfully managed with oral chlorambucil.

Case presentation

A 71-year-old Caucasian man presented to our facility with visual loss in his only functioning eye (left). On clinical examination, we found a conjunctival lesion with a choroidal infiltration and a secondary retinal detachment. Ultrasound and magnetic resonance imaging studies revealed a choroidal tumour mass and two other lesions around the optic nerve. Results from an incisional biopsy revealed a low-grade B-cell lymphoma (CD20+, CD43+, bcl2+, CD3-). A diagnosis of primary uveal lymphoma was made. Our patient was started on a chemotherapy regime with no effect, and then oral chlorambucil was administered, with a relatively good result. At 10 months after the start of chlorambucil treatment, a best-corrected visual acuity of 0.4 was recorded, the choroidal mass had practically disappeared and the extra-ocular lesions had shrunk.

Conclusions

In all, 61 to 80 cases of primary uveal lymphoma have already been described in the literature. Generally, it is an indolent tumor with a good prognosis. However, there are some reports of aggressive tumor behavior a few years after initial diagnosis (about eight percent of cases). Other treatment options are orbital irradiation at low doses (20 to 40 Gy) or steroid administration. This is the first documented report of the efficacy of oral chlorambucil in the treatment of primary uveal lymphoma.

Find in the abstract:

·         Background

·         Why is it important

·         Needs to be reported

Answer the questions:

1.       Is this the first report of this kind in the literature?

2.       What are brief details of what the patient(s) presented with?

3.       What the reader should learn from the case report?

4.       What the clinical impact will be?

5.       Is it an original case report of interest to a particular clinical specialty of medicine?

6.       Will it have a broader clinical impact across medicine?

7.       Are any teaching points identified?

Follow-up

·         Why abstract is the most important part for case published in electronic databases?

·         What are basics of abstract writing?