Карточка-задание по английскому языку на тему «MEDICAL WRITING: CASE ABSTRACT_432»
«MEDICAL WRITING: CASE ABSTRACT_432»
·What is a medical case report?
·What parts does it include?
·What is an abstract?
Read the abstract of the medical case
Pandemic 2009 H1N1 virus
infection associated with purpuric skin lesions: a case report
The influenza virus infection may
be severe in non-immune people. Common complications of influenza virus include
upper and lower respiratory tract infections, otitis media, myocarditis, acute
respiratory distress syndrome and multi-organ failure. There have been cases of
vasculitis following influenza vaccination, and rash and acute purpura may
occur in certain viral infections. To the best of our knowledge, there are no
reports concerning cases of systemic vasculitis associated with pandemic 2009
A 23-year-old Caucasian woman was
hospitalized at the "L. Spallanzani" National Institute for
Infectious Diseases in Rome, Italy. Clinical and radiological features including
laboratory findings of this case are illustrated. Notably, the patient had
fever, severe abdominal pain, hematuria, arthritis, and purpuric manifestations
associated with a normal platelet count. Nasopharyngeal and rectal swabs
revealed pandemic 2009 (H1N1) virus by
reverse-transcriptase-polymerase-chain-reaction assay. Routine laboratory
analyses showed elevated inflammatory parameters. The autoimmune panel tests
were normal. Steroid therapy associated with oseltamivir achieved an evident
and rapid improvement. On day seven the patient chose to leave the hospital
against medical advice.
Complications related to influenza
infection can be life threatening, particularly in immunocompromised patients.
Henoch-Schönlein purpura triggered by the novel influenza virus infection
could be an attractive pathogenetic hypothesis. We have discussed both the
diagnosis and the challenge of therapy protocols. Steroid therapy is part of
the management of severe vasculitis. Our case suggests that steroid therapy
associated with antivirals can prevent the risk of further complications such
as hemorrhage and multi-organ failure during severe vasculitis, without
enhancing the virulence of the influenza virus. The possible role of pandemic
2009 (H1N1) in the pathogenesis of hemorrhagic
manifestations should be further investigated.
Find in the abstract:
·Why is it important
·Needs to be reported
Answer the questions:
1.Is this the first report of this kind in the literature?
2.What are brief details of what the patient(s) presented with?
3.What the reader should learn from the case report?
4.What the clinical impact will be?
5.Is it an original case report of interest to a particular clinical
specialty of medicine?
6.Will it have a broader clinical impact across medicine?
7.Are any teaching points identified?
·Why abstract is the most important part for case
published in electronic databases?