Карточка-задание по английскому языку на тему «MEDICAL WRITING: CASE ABSTRACT_87»
«MEDICAL WRITING: CASE ABSTRACT_87»
·What is a medical case report?
·What parts does it include?
·What is an abstract?
Read the abstract of the medical case
hemoglobinuria in systemic lupus erythematosus: a case report
hemoglobinuria is an acquired disorder of hemopoiesis and is characterized by
recurrent episodes of intravascular hemolysis due to an increased sensitivity
to complement-mediated hemolysis. Systemic lupus erythematosus with paroxysmal
nocturnal hemoglobinuria is very rare. We report a case of paroxysmal nocturnal
hemoglobinuria that developed in a patient with systemic lupus erythematosus
and lupus nephritis.
A 29-year-old Mongolian woman had
systemic lupus erythematosus, which manifested only as skin lesions when she
was 12 years old. She had leg edema and proteinuria when she was 23 years old,
and a renal biopsy revealed lupus nephritis (World Health Organization type
IV). She had been treated with steroids and immunosuppressant therapy. At 29,
she had headaches, nausea, general fatigue, and severe pancytopenia and was
admitted to our hospital. A laboratory evaluation showed hemolytic anemia.
Further examination showed a neutrophil alkaline phosphatase score of 46
points, a CD55 value of 18%, and a CD59 value of 78.6%. The results of Ham test
and sugar water tests were positive. The constellation of symptoms throughout
the clinical course and the laboratory findings suggested paroxysmal nocturnal
To the best of our knowledge,
systemic lupus erythematosus with paroxysmal nocturnal hemoglobinuria is very
rare. Clinicians should be aware of the association between autoimmune and
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·Needs to be reported
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1.Is this the first report of this kind in the literature?
2.What are brief details of what the patient(s) presented with?
3.What the reader should learn from the case report?
4.What the clinical impact will be?
5.Is it an original case report of interest to a particular clinical
specialty of medicine?
6.Will it have a broader clinical impact across medicine?
7.Are any teaching points identified?
·Why abstract is the most important part for case
published in electronic databases?