Карточка-задание по английскому языку на тему «MEDICAL WRITING: CASE ABSTRACT_113»
«MEDICAL WRITING: CASE ABSTRACT_113»
·What is a medical case report?
·What parts does it include?
·What is an abstract?
Read the abstract of the medical case
associated with bilateral adrenal hyperplasia and ambiguous genitalia: a case
Many fetal malformations can occur
because of maternal diabetes. However, ambiguous genital organs have never been
reported as an associated finding in the literature. This is the first report
of associated ambiguous genital organ and bilateral adrenal hyperplasia in a
case of diabetic fetopathy.
A 19-year-old Thai primigravida
with familial history of diabetes mellitus (DM) was diagnosed as having
gestational DM type 2, based on 100 g oral glucose tolerance test, and was
poorly controlled with insulin injections. Delayed targeted ultrasonography at
28 weeks gestation revealed multiple fetal anomalies. The woman underwent low
transverse cesarean section at 30 weeks gestation due to preterm labor and
transverse lie. The newborn with ambiguous genitalia was delivered but expired
after birth. Autopsy findings revealed alobar holoprosencephaly, a prominent
forehead, hypotelorism, an absent nose, absent bilateral ears, median cleft lip
and palate, preaxial polydactyly of the right hand, accessory spleens, single
umbilical artery, markedly enlarged adrenal glands and ambiguous external
genitalia The subsequent fetal chromosomal study revealed 46,XX.
We describe a case of diabetic
fetopathy with classic facial malformation and preaxial hallucal polydactyly
which has been proposed as a marker of diabetic embryopathy. Bilateral adrenal
hyperplasia with ambiguous genitalia, an uncommon associated anomaly, was also
identified. It is controversial whether adrenal hyperplasia can be a novel
feature of diabetic fetopathy or just a coincidental finding. Further
observation and adequate investigation are needed in such cases.
Find in the abstract:
·Why is it important
·Needs to be reported
Answer the questions:
1.Is this the first report of this kind in the literature?
2.What are brief details of what the patient(s) presented with?
3.What the reader should learn from the case report?
4.What the clinical impact will be?
5.Is it an original case report of interest to a particular clinical
specialty of medicine?
6.Will it have a broader clinical impact across medicine?
7.Are any teaching points identified?
·Why abstract is the most important part for case
published in electronic databases?